Intra-Abdominal Infection (Sub-Category)

Intra-abdominal Infections Educational Module

Dr. Miranda So, BScPhm PharmD

Developed by:  Miranda So, BScPhm PharmD with contributions from the CAHO ASP Project Team


  • Source control is an important determinant of outcome in IAI.
  • Choice of empiric antibiotic therapy depends on they type of IAI, while taking into account the patient’s prior antibiotic exposure and risk of acquiring resistant organisms.
  • For healthcare-associated IAI, patient’s institutional length-of-stay and local (institutional) susceptibility data should be cosidered in determining empiric antibiotic therapy.
  • Duration of therapy is influenced by achievement of source control.  It should be no longer than 3-7 days if source control is achieved and patient is improving clinically.
  • Lack of clinical improvement should prompt further investigation for source of infection, rather than prolonged antimicrobial therapy.

PDF Link to Article:

Council of Academic Hospitals of Ontario (CAHO) Antimicrobial Stewardship in the Intensive Care Unit ARTIC Project: Intra-abdominal Infections Education Module